Abstract:
<em>Introduction:</em> Oxidative stress (OS) level is higher in individuals with Down syndrome (DS). Malondialdehyde (MDA) is a marker for lipid peroxidation and the effect of exercise training on MDA in DS patients is not well known. The aim of this study was to examine the effects of selected Spark Motor Program on MDA in boys with DS.<br /> <em>Material & Methods:</em> Twenty Down syndrome boys aged between 10~14 participated in this study as the subjects. The subjects were randomly divided into experimental group (n=10) or control group (n=10). The experimental group was performed selected Spark Motor Program 3 days a week for 8 weeks. MDA concentration was measured before and 48h after the intervention.<br /> <em>Results:</em> The results showed that MDA decreased after 8 weeks selected experimental in compare to the control group.<br /> <em>Conclusions:</em> In summary, Spark Motor Program that selected in this study decreases MDA of boys with DS.
Machine summary:
Spark Motor Program reduced oxidative stress in boys with Down syndrome Atefeh Jan Mohammadi1 and Mehrzad Moghadasi2* Received: 28 January 2018/ Accepted: 8 Mrch 2018 (1) MS in Exercise Physiology, Department of Exercise physiology, Marvdasht branch, Islamic Azad University, Marvdasht, Iran.
com Abstract Introduction: Oxidative stress (OS) level is higher in individuals with Down syndrome (DS).
The aim of this study was to examine the effects of selected Spark Motor Program on MDA in boys with DS.
Conclusions: In summary, Spark Motor Program that selected in this study decreases MDA of boys with DS.
Oxidative stress, Down syndrome, Malondialdehyde, Spark training 1.
In addition, the brain abnormalities observed in DS have been linked to an inherent oxidative stress (OS), for example, characteristics of accelerated aging and high incidence of hyperactivity, with accompanying attention deficits (6,7).
Thus the present study was conducted to examine the effect of 8 weeks selected Spark Motor Program on MDA in boys with DS.
Therefore, in this study, we tested the effects of selected Spark Motor Program on MDA in boys with DS.
5. Conclusion In conclusion, Spark Motor Program that selected in this study reduces MDA in boys with DS.
Further studies are recommended to detect the effect of Spark Motor Program on OS in different age groups of DS individuals.
Effect of Spark Motor Program on the development of gross motor skills in Down syndrome boys.
Aerobic exercise reduced oxidative stress in saliva of persons with Down syndrome.
Efficacy of selected treadmill training programme on oxidative stress in adolescents with Down syndrome.