خلاصه ماشینی:
"c o m I S S N (Online): 2322 – 4479 Original Article Received: 07/12/2013 Accepted: 29/03/2013 Liver ABCA1 Gene Expression in Male Rats: Effects of High-intensity Treadmill Running and Black Crataegus-pentaegyna (Siayh-Valik) Extraction 1Abbass Ghanbari-Niaki, 1Monireh Gholizadeh, 1Safieyh Ghanbari-Abarghooi, 2Fatemeh Roudbari, 3Mohammad Javad Chaichi 1.
ABSTRACT The purpose of the current study was to investigate the effect of a high- intensity treadmill running (8 weeks) with or without aqueous extraction of black Crataegus-Pentaegyna (Siyah -Valik) on liver ABCA1 mRNA expression and plasma HDL-C, total, and direct bilirubin concentration in male rats.
The current results show that high-intensity treadmill running affected liver ABCA1 mRNA expression in different directions in saline (increase) and SV (decrease) treated animals.
Key Words: ATP-binding cassette protein-A1 (ABCA1), HDL-C, Male Rats, High-intensity running, Black Crataegus-Pentaegyna (Siyah –Valik).
There is very less information about the effect of the black Crataegus Pentaegyna (Siyah-Valik) extraction on ABCA1 mRNA expression with or without a high-intensity treadmill running program.
The second purpose to see a possible change in ABCA1 could be accompanied with significant changes in plasma HDL, bilirubin total and direct concentrations to a high- intensity treadmill running programm and black crataegus pentaegyna (Siyah-Valik) in male rat.
CONCLUSION Taken together, the findings of the current study indicate that SV extraction enhanced plasma HDL levels, but the effect of SV at rest reduced by high intensity treadmill running in somewhat.
Heart ABCA1 and PPAR- α Genes Expression Responses in Male rats: Effects of High Intensity Treadmill Running Training and Aqueous Extraction of Black Crataegus-Pentaegyna."