چکیده:
A limited number of studies has been carried out concerning the combined effects of resistance training and saffron supplementation on cardiovascular risk factors. The aim of this study was to assess the effects of circuit resistance training with Crocus sativus (saffron) supplementation on plasma viscosity and fibrinogen. For this purpose, 44 healthy male subjects, based on individual characteristics and after homogenization, were divided into four groups, including water-training (WT; n=11), petal sweat–training (PST; n=10), bottom part of flower-training (BFT; n=11), and upper part of flower-training (UFT; n=12). Resistance training consisted of 12 stations (each station for 30 seconds with 40% of one repetition maximum) for 2 weeks (5 sessions per week). Saffron in the amount of 500 mg was used twice daily, i.e. in the morning and immediately after exercise. Blood samples were taken before and 48 hours after the last exercise session and were analyzed for fibrinogen and plasma viscosity. Significant differences were observed between groups in plasma levels of fibrinogen (P=0.01). The post hoc test showed significant differences between the UFT and PST groups and the UFT and BFT groups (respectively, P=0.04 and P=0.014). In the post-test, plasma fibrinogen had significantly decreased in the WT (P=0.005), PWT (P=0.003), and UFT (P=0.001) groups compared with pre-test data (within group difference). Moreover, plasma viscosity was significantly changed among groups (F3, 37=3.52, P=0.024). The post hoc test showed significant differences between the UFT and WT groups (P=0.037). In post-test data, plasma viscosity had significantly decreased in the WT (P=0.015) and UFT (P<0.001) groups compared with pre-test data. The present results show that circuit resistance training with saffron supplements can reduce cardiovascular risk factors (fibrinogen and plasma viscosity).
خلاصه ماشینی:
"Effects of Circuit Resistance Training with Crocus Sativus (Saffron) Supplementation on Plasma Viscosity and Fibrinogen 1Abbass Ghanbari-Niaki, 1Ayoub Saeidi, 1Mahdi Aliakbari-Beydokhti, 1Sadegh Ardeshiri, 1Sarkawt Kolahdouzi, 2Mohammad Javad Chaichi, 3Bijan Hedayati-Monfared 1.
The present results show that circuit resistance training with saffron supplements can reduce cardiovascular risk factors (fibrinogen and plasma viscosity).
Considering the conflicting findings about blood viscosity, plasma, and fibrinogen as significant indices in cardiovascular diseases, the simultaneous use of a food-drug before or after physical exercise, especially sequential circuit resistance exercises, can undoubtedly provide a new area to manage the correct usage of food supplementation with training.
Thus, considering the influence of resistance training on permanent increases in blood viscosity and plasma induced by increased fibrinogen, albumin, total protein, and hematocrit following resistance activities (21), this study sought to answer the questions of whether taking all parts of saffron confirm or reject the possible effects of saffron with short-term resistance training and whether supplementation with various parts of the saffron flower strengthens the anticoagulant effects of physical exercise, thereby having a protective effect.
It seems, therefore, that an upper part of saffron supplement coupled with short-term circuit resistance training can cause a greater reduction in plasma fibrinogen levels and platelets aggregation and consequently, a slight reduction in plasma viscosity.
Considering the results of this study, it can be concluded that saffron supplement use combined with two weeks of circuit resistance training can reduce cardiovascular risk factors (fibrinogen and plasma viscosity), although supplement with the upper part of saffron in combination with saffron caused a greater reduction in these risk factors."