چکیده:
Introduction: Galectin-3 (gal-3) is a member of the lectin
family that is associate with heart failure, including
myofibroblast proliferation, fibrogenesis, tissue repair,
inflammation, and ventricular remodeling. Although gal-3
increases after high intensity exercise, regular training may
attenuate these conditions. The aim of present study was to
investigate the effect of 8 weeks regular endurance training
on galectin-3 changes after a strenuous aerobic exercise.
Material and Methods: Eleven healthy young men (aged: 20.8
± 1.8 years; ± SD) volunteered to participate in this study.
All the subjects were performed Repeated High-Intensity
Endurance Test (RHIET) as a strenuous aerobic exercise.
Thereafter, the subjects were performed endurance training 3
days a week for 8 weeks at an intensity corresponding to 60-
75% individual heart rate reserve (HRR) for 30-45 min. After
the 8 weeks intervention, the RHIET was performed a gain.
Blood samples were taken at baseline (1st step), immediately
after the RHIET (2nd step), 48h after 8 weeks intervention
(3rd step) and immediately after the second RHIET (4th step).
Results: The results showed that gal-3 level was increased
after the first strenuous aerobic exercise (P<0.05). After 8
weeks exercise training, gal-3 was decreased compared to 2nd
step of blood sampling (P<0.05) and no significant change
was observed in gal-3 in this step compare to the baseline.
The results indicated that gal-3 level was lower after the
second strenuous aerobic exercise than compare to the after
the first strenuous aerobic exercise (P<0.05).
Conclusions: The results suggest regular endurance training
with specific intensity and duration utilized in this study,
attenuate gal-3 changes after single session of strenuous
aerobic exercise.
خلاصه ماشینی:
Effect of 8 weeks regular endurance training on galectin-3 changes after a strenuous aerobic exercise Nooshin Khajeian1 and Mehrzad Moghadasi2* Received: 14 Jun 2017/ Accepted: 18 July 2017 (1) Department of Exercise physiology, Marvdasht branch, Islamic Azad University, Marvdasht, Iran.
The aim of present study was to investigate the effect of 8 weeks regular endurance training on galectin-3 changes after a strenuous aerobic exercise.
All the subjects were performed Repeated High-Intensity Endurance Test (RHIET) as a strenuous aerobic exercise.
Results: The results showed that gal-3 level was increased after the first strenuous aerobic exercise (P Key words: Regular training, Galectin-3, Strenuous aerobic exercise, Heart failure 1.
Therefore, we evaluated the effect of 8 weeks regular endurance training on gal-3 changes after a strenuous aerobic exercise.
Although it has been reported that gal-3 concentration increases after acute and high-intensity aerobic exercise, the effect of regular endurance exercise on gal-3 level is not still clear.
Therefore, the aim of present study was to evaluate the effect of 8 weeks regular endurance training on gal-3 changes after a strenuous aerobic exercise.
The results in agreement with previous studies indicated that gal-3 concentration increase after a strenuous aerobic exercise (6-8).
Our results indicated that gal-3 concentration was decreased after 8 weeks regular endurance training and gal-3 level was lower after the second strenuous aerobic exercise compare to the first strenuous aerobic exercise (P baseline.
6. Conclusion In conclusion, the present study suggests that regular endurance training decreases gal-3 concentration induced by strenuous aerobic exercise.