ANNALS OF APPLIED SPORT SCIENCE–Special Issue
First National Congress of
"New Scientific Consequence for Iran’s Sport Development" Lahijan Branch, Islamic Azad University, 2014, 10-11 December
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ISSN (Online): 2322 – 4479Effects of Arbutin Supplementation on Liver Total Oxidant and Antioxidant Status Following a Period of Aerobic Exercise in the Liver of Alloxan-Induced Diabetic Rats
1Fatemeh Rashidpour* 2Parvin Farzanegi, 3Mohammad Taghipour
1. Rashidpour Fatemeh (M.SC): Department of Physical Education and Sports Sciences, Sari
Branch, Islamic Azad University, Sari, Iran.
2. Farzanegi Parvin (PhD): Assistant Professor, Department of Physical Education and Sports
Sciences, Sari Branch, Islamic Azad University, Sari, Iran.
3. Taghipour Mohammad (PhD): Associate Professor, Mobility impairment Research Center, Babol University of Medical Sciences, Babol, Iran.
Diabetes cause Exacerbated oxidative stress and reduced activity of the antioxidant defense system (1). Reactive oxygen species are produced in response to exercise and it seems that the use of antioxidant supplements reduces exercise-induced oxidative stress (2). In the present study, the effects of arbutin supplementation on total oxidant and antioxidant status (TOS&TAS) following a period of aerobic exercise in liver of diabetic rats were evaluated.
In this experimental study a total of 42 male Wistar rats with average weight of 195-220 gr. randomly divided into 6 groups named control, diabetes, diabetes-exercise, arbutin, diabetic- arbutin, diabetic-arbutin-exercise. Aerobic exercise was programmed as five sessions per week during 6 weeks and 5-36 min/day. Alloxan (90mg/km) was injected to make diabetic rats and blood glucose higher than 250 mg/dl has been considered as diabetic. After that the arbutin