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Effects of Arbutin Supplementation on Liver Total Oxidant and Antioxidant Status Following a Period of Aerobic Exercise in the Liver of Alloxan-Induced Diabetic Rats

نویسنده:

(2 صفحه - از 233 تا 234)

خلاصه ماشینی:

"c om ISSN (Online): 2322 – 4479Effects of Arbutin Supplementation on Liver Total Oxidant and Antioxidant Status Following a Period of Aerobic Exercise in the Liver of Alloxan-Induced Diabetic Rats 1Fatemeh Rashidpour* 2Parvin Farzanegi, 3Mohammad Taghipour 1. SC): Department of Physical Education and Sports Sciences, Sari Branch, Islamic Azad University, Sari, Iran. 2. Farzanegi Parvin (PhD): Assistant Professor, Department of Physical Education and Sports Sciences, Sari Branch, Islamic Azad University, Sari, Iran. In the present study, the effects of arbutin supplementation on total oxidant and antioxidant status (TOS&TAS) following a period of aerobic exercise in liver of diabetic rats were evaluated. CONCLUSIONS The results showed regular exercise cannot lead to complete inhibition of oxidation in the liver of diabetic rats by itself (3). Ghadiri, Soufi, F (2012), Effect Of Exercise On Diabetes-Induced Oxidative Strees In The Rat Hippocampus."

صفحه: از 233 تا 234
233 Annals of Applied Sport Science , Spring 2015, Volume 3 - Number 9

‌ ‌‌‌ANNALS‌ OF APPLIED SPORT SCIENCE–Special Issue

First National Congress of

"New Scientific Consequence‌ for‌ Iran‌’s Sport Development" Lahijan Branch, Islamic Azad University, 2014, 10-11 December

w w w . aas s j our nal. c om‌

ISSN (Online): 2322 – 4479Effects of Arbutin Supplementation on Liver Total Oxidant and Antioxidant‌ Status Following a Period of‌ Aerobic‌ Exercise in the Liver of Alloxan-Induced Diabetic Rats

1Fatemeh Rashidpour* 2Parvin Farzanegi, 3Mohammad Taghipour

1. Rashidpour Fatemeh (M.SC): Department of Physical Education and Sports Sciences, Sari

Branch, Islamic Azad University, Sari‌, Iran.

2. Farzanegi Parvin (PhD): Assistant Professor, Department of Physical Education and Sports

Sciences, Sari Branch, Islamic Azad University, Sari, Iran.

3. Taghipour Mohammad (PhD): Associate Professor, Mobility impairment Research Center, Babol University‌ of‌ Medical Sciences, Babol, Iran.

INTRODUCTION

Diabetes cause Exacerbated oxidative stress and reduced activity of the antioxidant defense system (1). Reactive oxygen species are produced in response to exercise and it seems‌ that‌ the use of antioxidant supplements reduces exercise-induced oxidative stress (2). In the present study, the effects of arbutin supplementation on total oxidant and antioxidant status (TOS&TAS) following‌ a period‌ of aerobic exercise in liver of diabetic rats were evaluated.

METHOD

In this experimental study a total of 42 male Wistar rats with average weight of 195-220 gr. randomly‌ divided‌ into‌ 6 groups named control, diabetes, diabetes‌-exercise‌, arbutin‌, diabetic- arbutin, diabetic-arbutin-exercise. Aerobic exercise was programmed as five sessions per week during 6 weeks and 5-36 min/day. Alloxan‌ (90mg‌/km‌) was injected to make diabetic rats and blood‌ glucose‌ higher than 250 mg/dl has been considered as diabetic. After that the arbutin

234 Annals of Applied Sport Science , Spring 2015, Volume 3 - Number 9