چکیده:
To investigate the effect of short-term vitamin E supplementation on some indicators of athletic performance and resting lipid peroxidation after a session of exhaustive exercise at sea level, 19 healthy male students with a mean age of 21.13 ± 1.2 years, weight of 66.94 ± 5.6 kg, body mass index of 21.95 ± 2.5 kg/m² and VO2max of 37.91 ± 4 ml/kg/min were selected and randomly divided into two groups: vitamin E (9 people) and placebo (10 people). The vitamin E group received one capsule containing 400 IU of alpha-tocopherol acetate daily, and the placebo group received 0.4 grams of starch for 14 days. Blood sampling was performed under completely similar conditions before and after supplementation, and each stage was performed twice, before and immediately after the exhaustive exercise test on the ergometer (starting with a workload of 25 watts and a speed of 50 rpm for 3 minutes, then adding 25 watts every 2 minutes until exhaustion). The thiobarbituric acid method was used to determine malondialdehyde levels. Data were analyzed using repeated measures ANOVA, LSD post-hoc test, and independent and paired t-tests at a significance level of P > 0.05. The results showed a non-significant increase in time to exhaustion and a significant increase in maximum oxygen consumption in the supplemented group, while changes in these two indicators were not significant between the two groups. In addition, performing exhaustive exercise in both groups was accompanied by a significant increase in the lipid peroxidation index (MDA), which significantly decreased with vitamin E supplementation both at rest and after exercise. On the other hand, intergroup changes in resting and post-exercise lipid peroxidation were significant after the supplementation period. Based on these findings, it can be said that short-term vitamin E supplementation may improve some indicators of athletic performance by reducing lipid peroxidation.
خلاصه ماشینی:
Since 1- Reactive Oxygen Species Antioxidant supplements are used by athletes as a means to neutralize oxidative stress resulting from exercise, and the effect of these substances has been investigated in numerous studies in various sports activities (2, 4, 18, 27, 30).
It can be hypothesized that vitamin E, as the most important antioxidant substance (11, 12, 19, 20), can be effective in empowering the cellular antioxidant system by neutralizing free radicals and, by preventing oxidative stress and lipid peroxidation, improve physical performance in such conditions.
(c): Indicates a significant difference compared to the similar stage before the supplementation period Refer to the image on the page Discussion and Conclusion Researchers believe that vitamin E, as the main antioxidant substance established in tissue membranes (8, 12, 23), neutralizes various radical species with a direct effect, and is considered an important strategy against oxidative stress and reduced cellular function (8, 12, 36).
In the present study, the effect of short-term (two-week) vitamin E supplementation on time to fatigue, maximum oxygen consumption, and lipid peroxidation in healthy men following a single bout of exhaustive exercise on a cycle ergometer at sea level was investigated.
Consequently, although the research hypothesis regarding the effect of vitamin E supplementation in preventing increased oxidative stress and lipid peroxidation and improving athletic performance is confirmed, further research is needed to confirm this view in individuals with different levels of physical fitness.
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