Abstract:
Introduction: The aim of this study was to examine the effects of 8 weeks aerobic training on dehydroepianderestrone sulfate (DHEA-S) and cortisol in female patients with
multiple sclerosis disease. Material & Methods: Twenty seven women with MS disease
in a range of 20-47 year of old and EDSS lower than 5.5 participated in this study as the subject. Subjects were divided into control group (n=14) or training group (n=13)
randomly. The training group performed aerobic training program, 3 days a week for 8 weeks according to 55-60 percentage of VO2max. The control group was in absolute rest
at the same time. Serum level of DHEA-S and cortisol were measured by ELISA kits before and after training.Results: The results showed that cortisol and DHEA-S
concentrations did not change significantly after the intervention.
Conclusions: In conclusion, the results suggest aerobic training with specific intensity and duration utilized in this study had not effects on cortisol and DHEA-S levels in female patients with MS.
Machine summary:
Introduction: The aim of this study was to examine the effects of 8 weeks aerobic training on dehydroepianderestrone sulfate (DHEA-S) and cortisol in female patients with multiple sclerosis disease.
Conclusions: In conclusion, the results suggest aerobic training with specific intensity and duration utilized in this study had not effects on cortisol and DHEA-S levels in female patients with MS.
1. Introduction During multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS), activation of the hypothalamo- pituitary-adrenal (HPA) axis is considered to modulate the immune system in such a way that the probability of recovery from a relapse is increased (1).
Najafi and Moghadasi (2016) indicated that cortisol level was decreased after 8 weeks yoga training in female patients with MS (18); however Hejazi et al.
Thus this study was done to examine the effects of 8 weeks aerobic training on DHEA-S and cortisol in female patients with MS disease.
Our results demonstrated that cortisol level had not significant changes after 8 weeks aerobic training in female patients with MS.
Contradictory to these results, Najafi and Moghadasi (2017) showed that cortisol level was decreased after 8 weeks yoga training in female patients with MS (18).
5. Conclusions Our results suggest aerobic training with specific intensity and duration utilized in this study had not effects on cortisol and DHEA-S levels in female patients with MS.
The effect of yoga training on enhancement of Adrenocorticotropic hormone (ACTH) and cortisol levels in female patients with multiple sclerosis.