Abstract:
Methods: A Randomized Controlled Trial was used to compare the efficacy of GCRT that of patients who receive treatment as usual (TAU). From Razi hospital in Tehran, 40 inpatient people with schizophrenia resistant to medication and persistent negative and positive symptoms were assigned. Patients were included if they were aged 25 to 55 years had diagnosis of schizophrenia for at least 2 years and were persistent to medication for 2 years. 20 of them received a 16 session’s treatment over 2months and 20other ones were in waiting list. All Patients received TAU throughout the study. In all, 40 completed treatment. The positive and negative symptoms scales, NOSIE & NCSE completed for all patients before, in the middle and after treatment. . Results: Spss 11.5 and multivariate repeated measure was used. There were significant differences between the GCBT and TAU on positive and negative symptoms of schizophrenia. Significant improvement were found in the severity and number of positive (P= 0/05) and negative (P= 0/001) symptoms in patients treated with GCRT. GCRT leaded to improvement in cognitive functions (p=0/001) but there was no change in behavioral functions. In control group there were no significant differences between three measures (pre, middle and post). Conclusion: GCRT is a useful adjunct therapy in the management of patients with schizophrenia resistant to medication in treating negative &positive symptoms as well as cognitive deficits.
Machine summary:
Original Article A Randomized Clinical Trial of Group Cognitive- Rehabilitation Ther- apy for Patients with Schizophrenia Resistant to Medication Neda Ali beigi1; Parvaneh Mohamadkhani, PhD.
University of social welfare and rehabilitation sciences, Tehran, Iran Objectives: Against the background of evidence-based treatments for schizophrenia resistant to medica- tion, the implementation of cognitive- Rehabilitation therapy (CRT) becomes more important, especially about patients who don’t response to medication.
This research investigates the efficacy of GCRT decreasing positive and negative symptoms of schizophrenia and improving cognitive function.
Conclusion: GCRT is a useful adjunct therapy in the management of patients with schizophrenia resistant to medication in treating negative &positive symptoms as well as cognitive deficits.
The present study attempts to determine the effi- cacy of face to face group cognitive rehabilitation therapy in a population of medication-resistant patients in the Razi hospital in Tehran, meeting diagnostic criteria for schizophrenia, and with negative symptoms of at least 2 year duration to overcome many of the limitations of previously published work.
(10-20) Results showed Group CRT for cognitive deficits is associated with negative and positive symp- toms with a high effectiveness (p<0/001) but there is not enough evidence for behavioral func- tion.
A randomized controlled trial of cognitive-behavior therapy for persis- tent symptoms in schizophrenia: A five-year follow-up.
C. Cognitive rehabilitation therapy for outpatients with chronic schizophrenia: a controlled and randomized study.
Effects of cogni- tive remediation therapies on psychotic symptoms and cognitive complaints in patients with schizophrenia and related disorders:A randomized study.